Microneedling and Platelet-Rich Plasma (PRP) Therapy

Microneedling with Rejuvapen®, also known as Collagen Induction Therapy, is a minimally invasive skin-rejuvenation procedure, aimed at stimulating collagen and elastin synthesis to reduce the appearance of fine lines, wrinkles, skin laxity, stretch marks, acne and traumatic scarring.

Microneedling involves creating numerous microscopic needle incisions to induce a controlled injury response within the tissue to trigger natural collagen and elastin production.

Micro-channels created by the treatment allow for optimal absorption of topical products (Hyaluronic Acid Serum) and Platelet Rich Plasma (PRP), enhancing their effects in the deeper layers of skin.

Platelet Rich Plasma (PRP) Therapy.

At the present time platelet-rich plasma (PRP) is widely applied in different clinical scenarios, such as orthopedics, ophthalmology and healing therapies, as a growth factor pool for improving tissue regeneration. PRP therapy has also rapidly become a highly sought-after non-surgical procedure for facial and skin rejuvenation all around the world.

PRP is a concentrated blood plasma that is enriched with platelets, containing 8 potent growth factors along with other cytokines that stimulate healing of soft tissue.

In the process of a PRP enhanced microneedling treatment, platelet-rich plasma is separated from the patient’s blood via centrifugation, and then applied to the treated area, causing a release of growth factors in the dermis, which, in turn, triggers stem cells in the dermis to produce new collagen, blood vessels, and skin cells.

Currently there are several PRP systems commercially marketed, which facilitate preparation of ready- to- apply platelet-rich suspensions. All operate on a small volume of drawn blood (20-60 mL) and on the principle of centrifugation. These systems differ widely in their ability to collect and concentrate platelets depending on the method and time of their centrifugation. As a result, suspensions of different concentration of platelets are obtained. Differences in the platelets concentration influence the diversity of growth factors concentration, determining the regenerative strength of PRP.

PRP devices can be usually divided into low- yield (2.5-3 times baseline concentration) and high-yield (5-9 times baseline concentration) systems based on a platelet concentration factor.

When considering a rejuvenating procedure enhanced by PRP, it is crucial to note the equipment used for PRP preparation, as it is one of the deciding factors for the efficacy of the treatment. 


PureSpin™PRP system at Juno Dermatology.                                                                

  • A high-yield system: platelet concentration up to 9.7 times baseline.
  • The fastest high –yield PRP system on the market: 2 spin cycles totaling 6 minutes of the preparation time.
  • Best value: highest volume of PRP gained with a smaller amount of blood drawn from the patient.
  • Highest platelet recovery: up to 93.8% — exceeds the recovery rates of other high-yield systems currently on the market.
  • Highest amount of deliverable platelets: deliverable platelets are the actual volume of viable platelets contained in a PRP sample – significantly higher than its closest competitor.


The core principle of microneedling is to cause superficial wounding to the skin, resulting in a natural repair process that begins to replace aging and damaged skin with new and healthy cells. Adding platelet-rich plasma intensifies this treatment, as the repair process is dramatically enhanced by the growth factors contained in PRP. Combining microneedling with PRP therapy results in a remarkable rejuvenating treatment that stands out among all the other state-of-the-art procedures currently offered.

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